Non-Narcotic Analgesics (Non-Opioids)

What they are: Non-narcotic analgesics are medications used to control pain and inflammation. They are available at drugstores without a prescription or by prescription when given at higher doses. Some types of these medications can be given during surgery to reduce post-surgical pain and lessen the need for narcotics.

Examples include: Non-prescription options: Tylenol (chemical name: acetaminophen); non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, Motrin, or Advil (chemical name: ibuprofen); and Aleve or Naprosyn (chemical name: naproxen sodium). Surgical options: Exparel (chemical name: bupivacaine liposome injectable suspension) and IV Tylenol (chemical name: acetaminophen).

What they’re used for: Non-opioids are used to treat acute or persistent pain that is mild to moderate. They also may be used in combination with other medications or therapies to treat moderate to severe pain.

How they’re taken: Most non-opioids are taken by mouth. Some are given by injection or IV before, during, or after a surgical procedure.

Possible side effects include:

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